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Original Article
Dementia and Neurocognitive Disorders 2008: 7: 1: 10-16

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50세 이상 성인에서 운동량과 인지기능 간의 관계
김상환∙홍승희∙최희정
을지대학교 의과대학 가정의학교실
The Relation between Exercise Status and Cognitive Function in Adults Aged 50 Years and Older
Sang-Hwan Kim, M.D., M.P.H., Seung-Hee Hong, M.D., Hee-Jeong Choi, M.D., Ph.D.
Department of Family Medicine, Eulji University School of Medicine, Daejeon, Korea
Background: Exercise is known to providephysical and psychological health benefits in adults. There have been many studies on the effects of exercise on cognitive function in older people but few have dealt with the effects of exercise on cognitive function in adults aged 50 yr and older. Methods: The subjects of this study were 380 men and women aged ≥50 yr who received health examination at a university hospital in Seoul during the period between December, 2004 and April, 2005. Exercise behavior was surveyed with questionnaires forthe frequency of aerobic exercises 30 min or longer per week for the latest 3 months. Those who exercised once a week or less were identified as the no-exercise group, those 2-3 times per week were grouped into the occasional exercise group, those 4-5 times per week were grouped into the moderate exercise group, and those 6 times or more per week were grouped into the frequent exercise group. Cognitive function was measured using Korean Mini-mental Status Examination (K-MMSE). Results: Of the male subjects, 44 (23.9%) fell into the no-exercise group, 44 (23.9%) into the occasional exercise group, 67 (36.4%) into the moderate exercise group, and 29 (15.8%) into the frequent exercise group. In the female population, the numbers were 91 (46.4%), 38 (19.4%), 43 (21.9%) and 24 (12.2%), respectively. The mean K-MMSE scores were 26.9±2.2 in the no-exercise group, 27.7±2.0 in the occasional exercise group, 28.1±1.7 in the moderate exercise group, and 28.9±0.9 in the frequent exercise group, thus showing that the scores increased with increases in exercise status (p<0.001). Using multiple regression analysis controlling for age, gender, academic qualification, smoking, drinking, cholesterol levels and prior disease histories such as hypertension and diabetes, we found that the K-MMSE scores in the moderate exercise group and the frequent exercise group were higher by 0.7 and 1.5, respectively, compared to that in the non-exercise group (p=0.002 and p<0.001, respectively). Conclusions: These findings suggest that frequent exercise is associated with higher cognitive functions in adults aged 50 yr and older. In future studies, we need to assesswhether this is the direct effect of exercise or an indirect effect from improving cardiovascular disease risk factors.
Key Words: Exercise, Cognitive functions, K-MMSE