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| Original Article | |||||
| Dementia and Neurocognitive Disorders 2010: 9: 1: 8-12 | |||||
| 치매선별검사로서 K-MMSE의 타당도 연구: 종합적인 신경심리학적 평가와의 비교 | |||||
|---|---|---|---|---|---|
| 오은아*∙강연욱*,†∙신준현‡∙연병길§ | |||||
| 강동성심병원 치매예방센터, 한림대학교 심리학과* 한림대학교성심병원 신경과† 강동성심병원 신경과‡, 정신과§ |
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| A Validity Study of K-MMSE as a Screening Test for Dementia: Comparison Against a Comprehensive Neuropsychological Evaluation | |||||
| Euna Oh, M.A.*, Yeonwook Kang, Ph.D.*,†, Joon Hyun Shin, M.D.‡, Byeong Kil Yeon, M.D.§ | |||||
| Dementia Prevention Center, Kangdong Sacred Heart Hospital, Seoul; Department of Psychology*, Hallym University, Chuncheon; Department of Neurology†, Hallym Sacred Heart Hospital†, Anyang; Departments of Neurology‡ and Neuropsychiatry§, Kangdong Sacred Heart Hospital, Seoul, Korea |
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| Background: Although the Korean-Mini Mental Status Examination (K-MMSE) has been widely used for screening dementia in clinics and other community settings, there has been little investigation into the validity of the K-MMSE. The present study was conducted to examine the validity of the K-MMSE as a dementia screening tool compared against a comprehensive neuropsychological evaluation. Methods: The subjects were 707 outpatients (261 men, 446 women; mean age=70.3±6.3 yr, mean education= 6.3±5.1 yr) who visited the neurology or psychiatry department with complaints of cognitive dysfunction. They were given the K-MMSE and a comprehensive neuropsychological test battery (Seoul Neuropsychological Screening Battery, SNSB). The subjects were classified into ‘‘Cognitive Impairment’’ and ‘‘No Cognitive Impairment’’groups based on the SNSB as well as the K-MMSE. Results: The agreement between classification based on the K-MMSE and the SNSB was examined. The sensitivity of K-MMSE for detecting cognitive impairments was 80.3% and the specificity was 70.3% (Positive predictive value 90.4%; Negative predictive value 50.7%). The false-positive rate was found to be higher for the subjects with low education. The majority of the subjects in the false-negative group showed prominent frontal/executive dysfunctions as well as memory impairment. Conclusions: These results showed that K-MMSE has high positive- and negative-false rates and a low negative predictive power. They suggest that the K-MMSE should be given with memory and frontalexecutive function tests for improving screening accuracy for dementia. | |||||
| Key Words: K-MMSE, Seoul Neuropsychological Screening Battery (SNSB), Sensitivity, Specificity, Positive predictive value, Negative predictive value | |||||
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