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Case Report
Dementia and Neurocognitive Disorders 2014: 13: 3: 79-82

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가벼운 기억력 장애를 주소로 내원한 비부수 종양성 자가면역 항체 음성 변연뇌염 1예
한상우·주재정·강진호,하상원·양영순
보훈공단 중앙보훈병원 신경과
Non-paraneoplastic Autoantibody-negative Limbic Encephalitis Characterized by Mild Memory Impairment: A Case Report
SangWoo Han, M.D., JaeJeong Joo, M.D., JinHo Kang, M.D., Sang won Ha, M.D., YoungSoon Yang, M.D.
Department of Neurology, VHS Medical Center, Seoul, Korea
Encephalitis that primarily involves limbic system structures such as the hippocampus and parahippocampal gyrus has been described in early papers, most commonly characterized by a subacute progressive impairment of short-term memory, psychiatric features and seizures. While these findings might be caused by viral infections or systemic autoimmune disorders, many patients with limbic encephalitis have an immune-mediated etiology (paraneoplastic or not) characterized with serum or CSF antineuronal antibodies. This case reports about non-paraneoplastic autoantibody-negative limbic encephalitis in which there are no detection of antigens and no evidence of tumors.
Key Words: Limbic encephalitis, Memory impairment, Non-paraneoplastic, Autoantibody negative
대한치매학회지 (Dementia and Neurocognitive Disorders)