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Original Article
Dementia and Neurocognitive Disorders 2018: 17: 1: 23-31

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The Effect of Cognitive Intervention on Cognitive Improvement in Patients with Dementia
Kyunghwa Jo ,1,* Jin Hyeong Jhoo ,1,2,3,* Young-Ju Mun , 3 Yeon Mi Kim ,3Sung Keun Kim ,4 Seongheon Kim ,4,5 Seung-Hwan Lee ,4,5 Jae-Won Jang 4,5
1Department of Psychiatry, Kangwon National University Hospital, Chuncheon, Korea 2Department of Psychiatry, Kangwon National University School of Medicine, Chuncheon, Korea 3Gangwon Provincial Dementia Center, Chuncheon, Korea 4Department of Neurology, Kangwon National University Hospital, Chuncheon. Korea 5Department of Neurology, Kangwon National University School of Medicine, Chuncheon, Korea
The Effect of Cognitive Intervention on Cognitive Improvement in Patients with Dementia
Kyunghwa Jo ,1,* Jin Hyeong Jhoo ,1,2,3,* Young-Ju Mun , 3 Yeon Mi Kim ,3Sung Keun Kim ,4 Seongheon Kim ,4,5 Seung-Hwan Lee ,4,5 Jae-Won Jang 4,5
1Department of Psychiatry, Kangwon National University Hospital, Chuncheon, Korea 2Department of Psychiatry, Kangwon National University School of Medicine, Chuncheon, Korea 3Gangwon Provincial Dementia Center, Chuncheon, Korea 4Department of Neurology, Kangwon National University Hospital, Chuncheon. Korea 5Department of Neurology, Kangwon National University School of Medicine, Chuncheon, Korea
Background and Purpose: The effect of cognitive intervention in patients with dementia is
inconsistent. This study sought to find out the effect of cognitive intervention by measuring
interval change between before and after intervention.
Methods: We evaluated cognitive changes according to clinical diagnostic group across
Gangwon province for 940 patients with dementia diagnosed at hospital clinics and
2,975 subjects without dementia. All subjects were treated with cognitive intervention.
They underwent a cognitive and mood assessment before and after intervention. We used
interval change of Mini-Mental State Examination (MMSE) scores as a primary measure of
interventional outcome.
Results: Changes in mean MMSE score were significantly different between the non￾dementia group and the dementia group (p=0.016), with changes of 0.7±2.4 and 1.0±3.7
points (±standard deviation), respectively. Cognitive improvement regarding completion of
session was significantly higher in the dementia group (p=0.001), with changes of 0.41±4.51
for uncompleted group and 1.30±3.22 points for completed ones. Lower initial MMSE scores,
lower age, and type of intervention were found to be independent predictive factors of
subsequent cognitive changes as indicated by mean MMSE scores.
Conclusions: These findings suggest that cognitive intervention might be useful for patients
with dementia. Their response to treatment might be related to the type of intervention.
Key Words: Cognitive Therapy; Dementia
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