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Anti-N-Methyl-D-Aspartate Receptor Encephalitis Presenting Progressive Dyslexia: A Case Report
Case Report
Dementia and Neurocognitive Disorders 2015: 14: 4: 176-179	전문보기
Kwang Hyun Pan, Jin Hee Kim, Byung-Jo Kim, Chan-Nyoung Lee
Department of Neurology, Korea University Anam Hospital, Seoul, Korea
Anti-N-Methyl-D-Aspartate Receptor Encephalitis Presenting Progressive Dyslexia: A Case Report
Kwang Hyun Pan, Jin Hee Kim, Byung-Jo Kim, Chan-Nyoung Lee
Department of Neurology, Korea University Anam Hospital, Seoul, Korea
Background Anti-N-methyl-D-aspartate (anti-NMDA) receptor encephalitis was discovered less than 10 years ago. Its symptoms and characteristics are not well-defined yet. We experienced a case of anti-NMDA receptor encephalitis with phonemic paraphasia and acalculia that were not classical characteristics. Case Report A 44-year-old woman started to show dyslexia, phonemic paraphasia, and dyscalculia. These symptoms were gradually worsening for over 30 days. Various brain images were not helpful for primary diagnosis. Anti-NMDA receptor encephalitis was confirmed in two different laboratories. The patient started to recover with various immunosuppressive therapies. Conclusions Anti-NMDA receptor encephalitis can have various symptoms, including phonemic paraphasia and acalculia.
Key Words: anti-N-methyl-D-aspartate receptor encephalitis, dyslexia, acaculia, paraphasia.