Case Report |
Dementia and Neurocognitive Disorders 2011: 10: 3: 102-105 |
전문보기
|
쉐그렌증후군과 항 갑상선 항체의 상승을 동반한 비혈관염 자가면역 염증성 뇌병증 1예 |
이성준, 손성연, 임태성, 문소영 |
아주대학교 의과대학 신경과학교실 |
A Case of Nonvasculitic Autoimmune Inflammatory Meningoencephalitis Accompanied by Sjögren’s Syndrome and Elevated Antithyroid Antibodies |
Seong Joon Lee, M.D., Sung Yeon Sohn, M.D., Tae Sung Lim, M.D., So Young Moon, M.D. |
Department of Neurology, Ajou University School of Medicine, Suwon, Korea |
Background: Nonvasculitic autoimmune inflammatory meningoencephalitis (NAIM) is known to be one of the causes of potentially reversible dementia. NAIM can be accompanied by various autoimmune diseases. Methods: A 65 year-old woman had been treated with stable bipolar disorder and presented with rapid cognitive decline, visual hallucination and myoclonus. Anti-thyroid antibodies were elevated. Her symptoms were responsive to steroid therapy. Her diagnostic evaluation also revealed Sjögren’s syndrome. Although her symptoms recovered, a manic episode reappeared and was responsive to psychiatric treatment. Conclusions: Patients presenting with rapidly progressive dementia should be thoroughly evaluated for the diagnosis of NAIM, a potentially treatable form of dementia, and the possible various underlying autoimmune etiologies. |
Key Words: Nonvasculitic autoimmune inflammatory meningoencephalitis, Sjögren’s syndrome, Steroid responsive encephalopathy associated with autoimmune thyroiditis, Bipolar disorder |
대한치매학회지 (Dementia and Neurocognitive Disorders)
|