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Case Report
Dementia and Neurocognitive Disorders 2011: 10: 3: 102-105

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쉐그렌증후군과 항 갑상선 항체의 상승을 동반한 비혈관염 자가면역 염증성 뇌병증 1예
이성준, 손성연, 임태성, 문소영
아주대학교 의과대학 신경과학교실
A Case of Nonvasculitic Autoimmune Inflammatory Meningoencephalitis Accompanied by Sjögren’s Syndrome and Elevated Antithyroid Antibodies
Seong Joon Lee, M.D., Sung Yeon Sohn, M.D., Tae Sung Lim, M.D., So Young Moon, M.D.
Department of Neurology, Ajou University School of Medicine, Suwon, Korea
Background: Nonvasculitic autoimmune inflammatory meningoencephalitis (NAIM) is known to be one of the causes of potentially reversible dementia. NAIM can be accompanied by various autoimmune diseases. Methods: A 65 year-old woman had been treated with stable bipolar disorder and presented with rapid cognitive decline, visual hallucination and myoclonus. Anti-thyroid antibodies were elevated. Her symptoms were responsive to steroid therapy. Her diagnostic evaluation also revealed Sjögren’s syndrome. Although her symptoms recovered, a manic episode reappeared and was responsive to psychiatric treatment. Conclusions: Patients presenting with rapidly progressive dementia should be thoroughly evaluated for the diagnosis of NAIM, a potentially treatable form of dementia, and the possible various underlying autoimmune etiologies.
Key Words: Nonvasculitic autoimmune inflammatory meningoencephalitis, Sjögren’s syndrome, Steroid responsive encephalopathy associated with autoimmune thyroiditis, Bipolar disorder
대한치매학회지 (Dementia and Neurocognitive Disorders)