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| Case Report | |||||
| Dementia and Neurocognitive Disorders 2015: 14: 2: 87-93 | |||||
| Longitudinal Clinical Changes of Non-Fluent/Agrammatic Primary Progressive Aphasia as Tau Spectrum Disorder: A Case Report | |||||
|---|---|---|---|---|---|
| Jin Soo Kim,1* Jae-Won Jang,1* Seong Heon Kim,1 Min Jeong Wang,2 Young Ho Park,2 SangYun Kim2 | |||||
| 1Department of Neurology, Kangwon National University Hospital, Chuncheon, Korea 2Clinical Neuroscience Center, Seoul National University Bundang Hospital, Department of Neurology, Seoul National University College of Medicine, Seongnam, Korea | |||||
| Longitudinal Clinical Changes of Non-Fluent/Agrammatic Primary Progressive Aphasia as Tau Spectrum Disorder: A Case Report | |||||
| Jin Soo Kim,1* Jae-Won Jang,1* Seong Heon Kim,1 Min Jeong Wang,2 Young Ho Park,2 SangYun Kim2 | |||||
| 1Department of Neurology, Kangwon National University Hospital, Chuncheon, Korea 2Clinical Neuroscience Center, Seoul National University Bundang Hospital, Department of Neurology, Seoul National University College of Medicine, Seongnam, Korea | |||||
| Background : Tauopathies are a group of diseases caused by the accumulation of hyperphosphorylated tau protein in the central nervous system. Previous studies have revealed that there is considerable overlap in clinical, pathological, and genetic features among different taupathies. Case Report : We report a patient with non-fluent/agrammatic primary progressive aphasia at the initial assessment. Over time, other symptoms belonging to corticobasal degeneration and progressive supranuclear palsy appeared in this patient. Conclusions : Clinical overlapping features in these disorders may represent different phenotypes of a single disease process. |
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| Key Words: taupathy, non-fluent/agrammatic primary progressive aphasia, corticobasal degeneration, progressive supranuclear palsy. | |||||
| 대한치매학회지 (Dementia and Neurocognitive Disorders) |
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