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| Case Report | |||||
| Dementia and Neurocognitive Disorders 2016: 15: 4: 165-169 | |||||
| Frontotemporal Dementia with Motor Neuron Disease in a Patient with Antiphospholipid Syndrome: A Case Report | |||||
|---|---|---|---|---|---|
| Yoon-Cheol Jeong, Jin-Seok Park, Seung-Hyun Kim, Hojin Choi | |||||
| Department of Neurology, Hanyang University College of Medicine, Seoul, Korea | |||||
| Frontotemporal Dementia with Motor Neuron Disease in a Patient with Antiphospholipid Syndrome: A Case Report | |||||
| Yoon-Cheol Jeong, Jin-Seok Park, Seung-Hyun Kim, Hojin Choi | |||||
| Department of Neurology, Hanyang University College of Medicine, Seoul, Korea | |||||
| Background Frontotemporal dementia (FTD) with motor neuron disease (MND) is a syndrome of progressive changes in behavior, language, muscle weakness and atrophy due to loss of function of neurons in the frontal and temporal lobes and in motor neurons. Etiology and pathogenesis of FTD with MND are still uncertain. Case Report A 71-year-old man presented with a 2-year history of progressive muscle weakness and cognitive deficits. We diagnosed this patient as FTD with MND by neurological examination, electromyography, brain imaging and neuro-psychological evaluation. We also confirmed antiphospholipid syndrome (APS) in this patient as a way to rule out secondary causes of MND. Conclusions This was a very rare case of FTD with MND in APS. We should focus study on the possible role of autoimmune pathogenesis in FTD with MND. |
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| Key Words: frontotemporal dementia, motor neuron disease, antiphospholipid syndrome. | |||||
| 대한치매학회지 (Dementia and Neurocognitive Disorders) |
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